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My child has

Because childhood should be simple ...

Paul W. Bowman, MD
Cook Children's Physician Network

Paul W. Bowman
Specialties:Hematology/Oncology
Education:University of Manitoba, Canada
Residency:University of Manitoba, Canada
Fellowship:St. Jude Children's Research Hospital, Tennessee
Board Certified:Pediatrics and Pediatric Hematology/Oncology

Locations:

1500 Cooper St.
Fort Worth, TX 76104
(682) 885-4007
Driving directions
1401 Ambler Ave., Ste. 101
Abilene, TX 79601
(325) 670-3910
Driving directions
701 W. Fifth, Ste. 2106
Odessa, Texas 79764
(432) 570-5693
Driving directions

Publications:


UI19129520
Mullighan, C. G., Su, X., Zhang, J., Radtke, I., Phillips, L. A., Miller, C. B. et al. (2009). Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. New England Journal of Medicine, 360(5), 470-480.
Whole author list: Mullighan,C.G.; Su,X.; Zhang,J.; Radtke,I.; Phillips,L.A.; Miller,C.B.; Ma,J.; Liu,W.; Cheng,C.; Schulman,B.A.; Harvey,R.C.; Chen,I.M.; Clifford,R.J.; Carroll,W.L.; Reaman,G.; BOWMAN,W.P.; Devidas,M.; Gerhard,D.S.; Yang,W.; Relling,M.V.; Shurtleff,S.A.; Campana,D.; Borowitz,M.J.; Pui,C.H.; Smith,M.; Hunger,S.P.; Willman,C.L.; Downing,J.R.; Children's Oncology,Group
UI19176441
Yang, J. J., Cheng, C., Yang, W., Pei, D., Cao, X., Fan, Y. et al. (2009). Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. JAMA, 301(4), 393-403.
Whole author list: Yang,J.J.; Cheng,C.; Yang,W.; Pei,D.; Cao,X.; Fan,Y.; Pounds,S.B.; Neale,G.; Trevino,L.R.; French,D.; Campana,D.; Downing,J.R.; Evans,W.E.; Pui,C.H.; Devidas,M.; BOWMAN,W.P.; Camitta,B.M.; Willman,C.L.; Davies,S.M.; Borowitz,M.J.; Carroll,W.L.; Hunger,S.P.; Relling,M.V.
UI18388178
Borowitz, M. J., Devidas, M., Hunger, S. P., BOWMAN, W. P., Carroll, A. J., Carroll, W. L. et al. (2008). Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study. Blood, 111(12), 5477-5485.
UI16184615
Borowitz, M. J., Pullen, D. J., Winick, N., Martin, P. L., BOWMAN, W. P., & Camitta, B. (2005). Comparison of diagnostic and relapse flow cytometry phenotypes in childhood acute lymphoblastic leukemia: implications for residual disease detection: a report from the children's oncology group. Cytometry Part B, Clinical Cytometry, 68(1), 18-24.
UI10676068
McMahon, L. W., Sealing, P. A., Mahoney DH, J., BOWMAN, W. P., & Sandler, E. (2000). Description of a multihospital process to develop a care path for the child with acute lymphoblastic leukemia. Journal of Pediatric Oncology Nursing, 17(1), 33-44.
UI10778944
Omura-Minamisawa, M., Diccianni, M. B., Batova, A., Chang, R. C., Bridgeman, L. J., Yu, J. et al. (2000). Universal inactivation of both p16 and p15 but not downstream components is an essential event in the pathogenesis of T-cell acute lymphoblastic leukemia. Clinical Cancer Research, 6(4), 1219-1228.
Whole author list: Omura-Minamisawa,M.; Diccianni,M.B.; Batova,A.; Chang,R.C.; Bridgeman,L.J.; Yu,J.; Pullen,J.; BOWMAN,W.P.; Yu,A.L.
UI 10573586
Trebo, M. M., Thorner, P. S., BOWMAN, W. P., & Weitzman, S. (1999). Long-term survival of a stage 4 neuroblastoma patient despite persistent bone marrow disease following autologous bone marrow transplantation. Medical & Pediatric Oncology, 33(6), 585-587.
UI 9065722
Bernstein, M. L., Abshire, T. C., Pollock, B. H., Devine, S., Toledano, S., Steuber, C. P. et al. (1997-Feb). Idarubicin and cytosine arabinoside reinduction therapy for children with multiple recurrent or refractory acute lymphoblastic leukemia: a Pediatric Oncology Group study. Journal of Pediatric Hematology/Oncology, 19(1), 68-72.
UI 9065717
Frankel, L. S., Ochs, J., Shuster, J. J., Dubowy, R., BOWMAN, W. P., Hockenberry-Eaton, M. et al. (1997-Feb). Therapeutic trial for infant acute lymphoblastic leukemia: the Pediatric Oncology Group experience (POG 8493). Journal of Pediatric Hematology/Oncology, 19(1), 35-42.
UI 9324339
Brecher, M. L., Schwenn, M. R., Coppes, M. J., BOWMAN, W. P., Link, M. P., Berard, C. W. et al. (1997). Fractionated cylophosphamide and back to back high dose methotrexate and cytosine arabinoside improves outcome in patients with stage III high grade small non-cleaved cell lymphomas (SNCCL): a randomized trial of the Pediatric Oncology Group. Medical & Pediatric Oncology, 29(6), 526-533.
UI 9193353
Farrow, A. C., Buchanan, G. R., Zwiener, R. J., BOWMAN, W. P., & Winick, N. J. (1997). Serum aminotransferase elevation during and following treatment of childhood acute lymphoblastic leukemia. Journal of Clinical Oncology, 15(4), 1560-1566.
UI 9041170
Sandler, E. S., Friedman, D. J., Mustafa, M. M., Winick, N. J., BOWMAN, W. P., & Buchanan, G. R. (1997). Treatment of children with epipodophyllotoxin-induced secondary acute myeloid leukemia. Cancer, 79(5), 1049-1054.
UI 8648381
BOWMAN, W. P., Shuster, J. J., Cook, B., GRIFFIN, T. C., Behm, F., Pullen, J. et al. (1996). Improved survival for children with B-cell acute lymphoblastic leukemia and stage IV small noncleaved-cell lymphoma: a pediatric oncology group study. Journal of Clinical Oncology, 14(4), 1252-1261.
UI 8874342
Winick, N., Shuster, J. J., BOWMAN, W. P., Borowitz, M., Farrow, A., Jacaruso, D. et al. (1996). Intensive oral methotrexate protects against lymphoid marrow relapse in childhood B-precursor acute lymphoblastic leukemia.[see comment]. Journal of Clinical Oncology, 14(10), 2803-2811.
UI CN-00466963
Schwenn, M. R., BOWMAN, W. P., Shuster, J., & Pediatric Oncology, G. (1995). Equivalent tolerance of high dose cytosine arabinoside (HD-Ara-C) by bolus versus continuous infusion (CI) in a randomized trial for b-cell acute lymphoblastic leukemia (B-ALL) and diffuse undifferentiated lymphoma (DUL) [abstract]. Proceedings of the American Society of Clinical Oncology, 14, 409.
UI 8084306
GRIFFIN, T. C., BOWMAN, W. P., Winick, N. J., & Buchanan, G. R. (1994). Treatment of advanced stage diffuse, small non-cleaved cell lymphoma in childhood: further experience with total therapy B. Medical & Pediatric Oncology, 23(5), 393-399.
UI 8083718
Sadowitz, P. D., Dubowy, R., Souid, A., Pollock, B. H., Weinstein, H., Parmley, R. T. et al. (1994). Phase I trial of continuous infusion carboplatin and etoposide in children with refractory acute leukemia: a Pediatric Oncology Group study. Journal of Clinical Oncology, 12(9), 1969-1973.
UI 8319201
Felix, C. A., Winick, N. J., Negrini, M., BOWMAN, W. P., Croce, C. M., & Lange, B. J. (1993). Common region of ALL-1 gene disrupted in epipodophyllotoxin-related secondary acute myeloid leukemia. Cancer research, 53(13), 2954-2956.
UI 8426196
Winick, N. J., McKenna, R. W., Shuster, J. J., Schneider, N. R., Borowitz, M. J., BOWMAN, W. P. et al. (1993). Secondary acute myeloid leukemia in children with acute lymphoblastic leukemia treated with etoposide.[see comment]. Journal of Clinical Oncology, 11(2), 209-217.
UI 1552746
Pui, C. H., Simone, J. V., Hancock, M. L., Evans, W. E., Williams, D. L., BOWMAN, W. P. et al. (1992). Impact of three methods of treatment intensification on acute lymphoblastic leukemia in children: long-term results of St Jude total therapy study X. Leukemia, 6(2), 150-157.
UI 1279710
Truly, M., Williams, J., Stearnes, L., Wood, L., BOWMAN, W. P., & Friedman, D. J. (1992). Volume depletion of bone marrow using gravity sedimentation in hydroxyethyl starch for the pediatric allogeneic transplant patient. Progress in Clinical & Biological Research, 377, 327-332.
UI 1734087
Winick, N. J., BOWMAN, W. P., Kamen, B. A., Roach, E. S., Rollins, N., Jacaruso, D. et al. (1992). Unexpected acute neurologic toxicity in the treatment of children with acute lymphoblastic leukemia. Journal of the National Cancer Institute, 84(4), 252-256.
UI 1777415
Douglass, E. C., Rowe, S. T., Valentine, M., Parham, D. M., Berkow, R., BOWMAN, W. P. et al. (1991). Variant translocations of chromosome 13 in alveolar rhabdomyosarcoma. Genes, chromosomes & cancer, 3(6), 480-482.
UI 1809236
Schneider, N. R., BOWMAN, W. P., & Frenkel, E. P. (1991). Translocation (3;21)(q26;q22) in secondary leukemia. Report of two cases and literature review. Annales de Genetique, 34(3-4), 256-263.
UI 2804898
Brown, R. E., Alade, S. L., Wu, M. C., Wu, F. M., & BOWMAN, W. P. (1989). Lipoperoxidation and T-cell leukemia of childhood. Effects of indomethacin. Cancer, 64(10), 2090-2095.
UI 3164174
Alade, S. L., Brown, R. E., & BOWMAN, W. P. (1988). Serum vitamin A status in acute lymphocytic leukemia of childhood. Annals of Clinical & Laboratory Science, 18(2), 155-161.
UI 3422333
Pui, C. H., BOWMAN, W. P., Ochs, J., Dodge, R. K., & Rivera, G. K. (1988). Cyclic combination chemotherapy for acute lymphoblastic leukemia recurring after elective cessation of therapy. Medical & Pediatric Oncology, 16(1), 21-26.
UI 3478116
Brown, R. E., BOWMAN, W. P., D'Cruz, C. A., Pick, T. E., & Champion, J. E. (1987). Endoperoxidation, hyperprostaglandinemia, and hyperlipidemia in a case of erythrophagocytic lymphohistiocytosis. Reversal with VP-16 and indomethacin. Cancer, 60(10), 2388-2393.
UI 3481040
Evans, W. E., Abromowitch, M., Crom, W. R., Relling, M. V., BOWMAN, W. P., Pui, C. H. et al. (1987). Clinical pharmacodynamic studies of high-dose methotrexate in acute lymphocytic leukemia. NCI Monographs, (5), 81-85.
UI 3672403
van Eys, J., BOWMAN, W. P., Britton, H. A., Buchanan, G. R., Fernbach, D. J., Haggard, M. E. et al. (1987). Pediatric cancers. Pediatric Oncology Workgroup, Legislative Task Force on Cancer in Texas. Texas medicine, 83(9 Pt 2), 24-45.
UI 3456079
Evans, W. E., Crom, W. R., Abromowitch, M., Dodge, R., Look, A. T., BOWMAN, W. P. et al. (1986). Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effect. New England Journal of Medicine, 314(8), 471-477.
UI 2945495
Miale, T. D., Nasrallah, A. G., Lobel, S. A., Demian, S., & BOWMAN, W. P. (1986). Natural killer cell activity and ultrastructure in myeloproliferative reactions in infants with Down's syndrome. American Journal of Pediatric Hematology/Oncology, 8(3), 191-199.
UI 3491184
Murphy, S. B., BOWMAN, W. P., Abromowitch, M., Mirro, J., Ochs, J., Rivera, G. et al. (1986). Results of treatment of advanced-stage Burkitt's lymphoma and B cell (SIg+) acute lymphoblastic leukemia with high-dose fractionated cyclophosphamide and coordinated high-dose methotrexate and cytarabine. Journal of Clinical Oncology, 4(12), 1732-1739.
UI 3859585
Abromowitch, M., BOWMAN, W. P., Ochs, J., & Rivera, G. (1985). Etoposide (VP-16) with prednisone and vincristine for the treatment of refractory acute lymphoblastic leukemia. Journal of Clinical Oncology, 3(6), 789-792.
UI 3885465
BOWMAN, W. P. (1985). Advances in the management of childhood leukemia. Texas medicine, 81(3), 39-44.
UI 3872347
Kalwinsky, D. K., Roberson, P., Dahl, G., Harber, J., Rivera, G., BOWMAN, W. P. et al. (1985). Clinical relevance of lymphoblast biological features in children with acute lymphoblastic leukemia. Journal of Clinical Oncology, 3(4), 477-484.
UI 3158360
Look, A. T., Roberson, P. K., Williams, D. L., Rivera, G., BOWMAN, W. P., Pui, C. H. et al. (1985). Prognostic importance of blast cell DNA content in childhood acute lymphoblastic leukemia. Blood, 65(5), 1079-1086.
UI 3905592
Murphy, S. B., BOWMAN, W. P., Hustu, H. O., & Berard, C. W. (1985). Advanced stage (III-IV) Burkitt's lymphoma and B-cell acute lymphoblastic leukaemia in children: kinetic and pharmacologic rationale for treatment and recent results (1979-1983). IARC scientific publications, (60), 405-418.
UI 3861494
Murphy, S. B., Dahl, G. V., Look, A. T., Ochs, J., Abromowitch, M., Pui, C. H. et al. (1985). Recent results from Total Therapy Study X for standard and high risk acute lymphoblastic leukemia in children: recognition of new clinical and biologic risk features. Haematology & Blood Transfusion, 29, 78-81.
UI 2863443
Pui, C. H., Dahl, G. V., BOWMAN, W. P., Rao, B. N., Abromowitch, M., Ochs, J. et al. (1985). Elective testicular biopsy during chemotherapy for childhood leukaemia is of no clinical value. Lancet, 2(8452), 410-412.
UI 3862434
Pui, C. H., Dodge, R. K., Dahl, G. V., Rivera, G., Look, A. T., Kalwinsky, D. et al. (1985). Serum lactic dehydrogenase level has prognostic value in childhood acute lymphoblastic leukemia. Blood, 66(4), 778-782.
UI 6589364
BOWMAN, W. P., Aur, R. J., Hustu, H. O., & Rivera, G. (1984). Isolated testicular relapse in acute lymphocytic leukemia of childhood: categories and influence on survival. Journal of Clinical Oncology, 2(8), 924-929.
UI 6141424
Evans, W. E., Crom, W. R., Stewart, C. F., BOWMAN, W. P., Chen, C. H., Abromowitch, M. et al. (1984). Methotrexate systemic clearance influences probability of relapse in children with standard-risk acute lymphocytic leukaemia. Lancet, 1(8373), 359-362.
UI 6593435
Ochs, J., Sinkule, J. A., Danks, M. K., Look, A. T., BOWMAN, W. P., & Rivera, G. (1984). Continuous infusion high-dose cytosine arabinoside in refractory childhood leukemia. Journal of Clinical Oncology, 2(10), 1092-1097.
UI 6589042
Pui, C. H., Aur, R. J., BOWMAN, W. P., Dahl, G. V., Dodge, R. K., George, S. L. et al. (1984). Failure of late intensification therapy to improve a poor result in childhood lymphoblastic leukemia. Cancer research, 44(8), 3593-3598.
UI CN-00207076
BOWMAN, W. P., Ochs, J., Pui, C. H., Kalwinsky, D. K., Abromowitch, M., & Aur, R. J. (1983). New directions of St. Jude Total-therapy protocols: study X for standard-risk childhood acute lymphoblastic leukemia. Leukemia research, 7, 203-211.
UI 6644427
Buchanan, G. R., BOWMAN, W. P., & Smith, S. J. (1983). Recurrent cerebral ischemia during hypertransfusion therapy in sickle cell anemia. Journal of Pediatrics, 103(6), 921-923.
UI 6600662
Evans, W. E., Hutson, P. R., Stewart, C. F., Cairnes, D. A., BOWMAN, W. P., Rivera, G. et al. (1983). Methotrexate cerebrospinal fluid and serum concentrations after intermediate-dose methotrexate infusion. Clinical Pharmacology & Therapeutics, 33(3), 301-307.
UI 6199470
Ochs, J. J., Parvey, L. S., Whitaker, J. N., BOWMAN, W. P., Ch'ien, L., Campbell, M. et al. (1983). Serial cranial computed-tomography scans in children with leukemia given two different forms of central nervous system therapy. Journal of Clinical Oncology, 1(12), 793-798.
UI 6583320
Pui, C. H., Jackson, C. W., Chesney, C., Lyles, S. A., BOWMAN, W. P., Abromowitch, M. et al. (1983). Sequential changes in platelet function and coagulation in leukemic children treated with L-asparaginase, prednisone, and vincristine. Journal of Clinical Oncology, 1(6), 380-385.
UI 6583322
Rivera, G., George, S. L., BOWMAN, W. P., Kalwinsky, D., Ochs, J., Dahl, G. V. et al. (1983). Second central nervous system prophylaxis in children with acute lymphoblastic leukemia who relapse after elective cessation of therapy. Journal of Clinical Oncology, 1(8), 471-476.
UI 6977384
Bernard, A., Murphy, S. B., Melvin, S., BOWMAN, W. P., Caillaud, J., Lemerle, J. et al. (1982). Non-T, non-B lymphomas are rare in childhood and associated with cutaneous tumor. Blood, 59(3), 549-554.
UI 6952944
Dow, L. W., Chang, L. J., Tsiatis, A. A., Melvin, S. L., & BOWMAN, W. P. (1982). Relationship of pretreatment lymphoblast proliferative activity and prognosis in 97 children with acute lymphoblastic leukemia. Blood, 59(6), 1197-1202.
UI 6959800
Evans, W. E., Stewart, C. F., Hutson, P. R., Cairnes, D. A., BOWMAN, W. P., Yee, G. C. et al. (1982). Disposition of intermediate-dose methotrexate in children with acute lymphocytic leukemia. Drug intelligence & clinical pharmacy, 16(11), 839-842.
UI 6950939
Mauer, A. M., BOWMAN, W. P., Dow, L. W., Look, A. T., & Williams, D. (1982). Acute lymphocytic leukemia: biological markers of clinical response. Journal of Cellular Physiology - Supplement, 1, 127-132.
UI 6181873
Rivera, G., BOWMAN, W. P., Look, A. T., Evans, W. E., Kalwinsky, D., & Dahl, G. V. (1982). Single-agent and combination chemotherapy with etoposide in the acute leukemias of childhood. Cancer treatment reviews, 9(Suppl), 53-57.
UI 6958957
Rivera, G., BOWMAN, W. P., Murphy, S. B., Dahl, G. V., Aur, R. J., Kalwinsky, D. K. et al. (1982). VM-26 with prednisone and vincristine for treatment of refractory acute lymphocytic leukemia. Medical & Pediatric Oncology, 10(5), 439-446.
UI 7083458
Rivera, G., Dahl, G. V., Murphy, S. B., BOWMAN, W. P., Aur, R. J., Avery, T. L. et al. (1982). VM26 therapy in children with drug-refractory lymphocytic leukemia. Cancer Chemotherapy & Pharmacology, 7(2-3), 169-172.
UI 6956375
Williams, D. L., Tsiatis, A., Brodeur, G. M., Look, A. T., Melvin, S. L., BOWMAN, W. P. et al. (1982). Prognostic importance of chromosome number in 136 untreated children with acute lymphoblastic leukemia. Blood, 60(4), 864-871.
UI 6947688
Ali, S. K., BOWMAN, W. P., & Aur, R. J. (1981). Increased radiation sensitivity of fibroblasts in ataxia telangiectasia with acute lymphocytic leukemia. American Journal of Diseases of Children, 135(12), 1142-1143.
UI 7006781
BOWMAN, W. P. (1981). Childhood acute lymphocytic leukemia: progress and problems in treatment. Canadian Medical Association journal, 124(2), 129-142.
UI 6175993
BOWMAN, W. P., & Mauer, A. (1981). The role of cell markers in the management of leukemia. Progress in hematology, 12, 165-185.
UI 6975162
BOWMAN, W. P., Melvin, S. L., Aur, R. J., & Mauer, A. M. (1981). A clinical perspective on cell markers in acute lymphocytic leukemia. Cancer research, 41(11 Pt 2), 4794-4801.
UI 6940627
Brodeur, G. M., Williams, D. L., Look, A. T., BOWMAN, W. P., & Kalwinsky, D. K. (1981). Near-haploid acute lymphoblastic leukemia: a unique subgroup with a poor prognosis? Blood, 58(1), 14-19.
UI 7018672
Kalwinsky, D. K., Weatherred, W. H., Dahl, G. V., BOWMAN, W. P., Melvin, S. L., Coleman, M. S. et al. (1981). Clinical utility of initial terminal deoxynucleotidyl transferase determinations in childhood acute leukemias. Cancer research, 41(7), 2877-2881.
UI 6454771
Pui, C. H., Burghen, G. A., BOWMAN, W. P., & Aur, R. J. (1981). Risk factors for hyperglycemia in children with leukemia receiving L-asparaginase and prednisone. Journal of Pediatrics, 99(1), 46-50.
UI 6987847
BOWMAN, W. P., Melvin, S., & Mauer, A. M. (1980). Cell markers in lymphomas and leukemias. Advances in Internal Medicine, 25, 391-425.
UI 6932995
Rivera, G., Dahl, G. V., BOWMAN, W. P., Avery, T. L., Wood, A., & Aur, R. J. (1980). VM-26 and cytosine arabinoside combination chemotherapy for initial induction failures in childhood lymphocytic leukemia. Cancer, 46(8), 1727-1730.
UI 6154821
Veit, B. C., Melvin, S. L., & BOWMAN, W. P. (1980). Identification of a leukemia-associated antigen of human acute lymphocytic leukemia. Journal of the National Cancer Institute, 64(6), 1321-1328.
UI 538556
Aur, R. J., Hustu, H. O., Verzosa, M., Johnson, W. W., Simone, J., Rivera, G. et al. (1979). ["Total therapy" for localized and regional malignant non-Hodgkin's lymphoma of children. A second look (author's transl)]. Sangre, 24(6), 1031-1042.

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