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Hyperinsulinism (HI) is a rare, and often severe, genetic disorder. It is the most common cause of hypoglycemia (low blood sugar) in infants more than 3 days old, as well as children. If not treated, these children are at risk for seizures or even permanent brain damage. Finding the right care is very important in preventing irreversible damage and improving quality of life.

A rare condition

Only about one in 25,000 to 50,000 children are born with it each year. Hyperinsulinism is genetic, and there are many different types. Depending on the type of hyperinsulinism your child has, symptoms may be present at birth or may not appear until later. Some forms are temporary and go away on their own. Others may require surgery, and some will need treatment for a lifetime. Fortunately, most of the long-term forms become easier to treat as your child gets older.

World renowned care

When you choose one of the leading hyperinsulinism programs available today for your new baby, you expect a world-class health care center with advanced neonatal intensive care. That's exactly what you'll find here.


Cook Children's is a level IV NICU, which means we offer the highest level of NICU care possible. We're able to provide care for the smallest preemies and medically fragile newborn babies, as well as provide special treatments, surgeries and services available at only a handful of NICUs nationwide.

Our single room settings are part of our advanced care. Studies show that premature and critically ill infants who are cared for in a single room setting have better long-term outcomes. These tiny patients are shown to grow better, and go home quicker. Cook Children's NICU is currently the largest of its kind in the nation, and one of the few that can accommodate twins, triplets, and even quads in a single room. So even if you're expecting multiples who will need specialized medical attention, your babies won't be separated and you won't have to leave their sides. It's the highest level of individual care in a single room.

Nationally recognized program

Having a tiny new baby with a serious illness is complicated enough. Having the top specialists taking care of your baby in one of the nation's leading NICUs can help make things a little simpler. When it comes to caring for newborns with hyperinsulinism, Cook Children's NICU is a special place. We have a dedicated NICU unit for babies with hyperinsulinism. The unit is equipped with the most advanced technology and a highly skilled medical team who specialize in hyperinsulinism, newborns and endocrinology.

World-renowned hyperinsulinism care is here

We're here to help.

If you are interested in scheduling a tour of our NICU, please call 682-885-4375. You can find information on how to refer a patient or other NICU contact information here.