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Comprehensive Epilepsy Program

Meet Helen and hear how the Cook Children's epilepsy team keeps her on her toes.

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Cook Children's Comprehensive Epilepsy Program is one of the leading and most advanced pediatric epilepsy programs in the country. Our program coordinates the skills of a highly specialized team of experts across neurosciences and Cook Children's Health Care System. This team is made up of epileptologists, neurologists, neurosurgeons, neuropsychologists, nurse specialists, EEG technologists, nutritionists, nurse educators, social workers and Child Life specialists, all working together to ensure children with epilepsy receive the most accurate diagnosis and advanced treatment available.

Why Choose Cook Children's Epilepsy Program

Our program sees more than 13,000 infants and children with seizures each year. Annually, we perform more than 6,000 EEGs and 40-50 epilepsy surgeries, making Cook Children's Comprehensive Epilepsy Program one of the busiest pediatric epilepsy centers in the nation. And with specialized diagnostic tools, like our MEG, the newest generation of advanced imaging technology is now available to even our youngest patients.

Using both medical and surgical treatments, the program offers some of the highest level of services to patients with epilepsy.

The National Association of Epilepsy Centers recognizes Cook Children's Comprehensive Epilepsy Program as a Level 4 Pediatric Epilepsy Center. Level 4 epilepsy centers have the professional expertise and facilities to provide the highest level medical and surgical evaluation and treatment for patients with complex epilepsy.

Our team approach

The epilepsy team meets weekly to review individual epilepsy cases. At these meetings, epileptologists, neurologists, neurosurgeons, neuropsychologists and neuroradiologists review patient histories, physicals, neuroimaging, and neurodiagnostic tests. The team considers underlying diagnoses and the effectiveness and side effects of current management, as well as treatment options and controversies, before making a decision on the best epilepsy care. Careful consideration is given to neuropsychological, speech and psychiatric evaluations. Ultimately, the team makes their decision, and the attending physician, the patient, and his or her family are consulted in order to make the final medical or surgical treatment decision.

Dr. Hansen performs endoscopic brain surgery

Pioneering surgery disconnects left and right brain to reduce and even prevent seizures

Cook Children’s neurosurgeon, Daniel Hansen, M.D. talks about a pioneering approach to epilepsy surgery. Using an endoscopic method for corpus callosotomy, this minimally invasive procedure helps improve operating time, recovery time, and has the same chance of seizure freedom post-surgery as traditional callosotomy.

The physicians and surgeons who provide this care are also involved in clinical research to discover new treatments for pediatric epilepsy. Cook Children's neuroscience investigators are enrolling patients into multiple clinical trials of medications and medical devices, and the list continues to grow. Our neuroscientists' clinical research has helped develop treatments for many children with epilepsy who had no hope of living seizure-free.

Meet our team

Epilepsy Monitoring Unit (EMU)

Our state-of-the-art Epilepsy Monitoring Unit (EMU) is an important component of the comprehensive evaluation and integrated care of patients with epilepsy and recurrent unprovoked spells. More than 800 children have been admitted to our 10-bed unit, designed with children in mind and capable of performing wireless electroencephalograms (EEGs) that allow the children to continue their normal activities while in the unit.

The EMU is part of the medical center's Neurophysiology program, and performs:

  • EEGs
  • EEGs (Spanish)
  • Video EEGs (VEEG)
  • Electrocorticography
  • Cortical mapping and cortical stimulation procedures
  • Inpatient, outpatient and intraoperative testing
    • Brain stem auditory evoked potentials (BAEP)
    • Visual evoked potentials (VEP)
    • Somatosensory evoked potentials (SSEP)
    • Motor evoked potentials (MEP)
    • Electromyography (EMG) and nerve conduction studies (NCS)

Our Epilepsy Program also has sophisticated neuroimaging capabilities including:

  • Magnetoencephalography (MEG)
  • Magnetic Resonance Imaging (MRI) using specialized epilepsy protocols
  • Magnetic Resonance-Spectroscopy (MR-Spectroscopy)
  • Functional MRI (fMRI) is different than MRI in that it allows doctors to see brain activity when a child is functions such as language or problem solving
  • Diffusion Tensor Imaging (DTI) that can map white matter tracts
  • Inter-ictal and ictal Single Photon Emission Computerized Tomography (SPECT) scan
  • Positron Emission Tomography (PET) scan
  • Intracarotid Amobarbital Procedure (IAP), also known as the Wada test(Spanish version)
  • Intraoperative MRI
    • Cook Children's is one of a handful of children's hospitals in the country with this technology
    • Provides the surgeon with accurate digital images of changing brain anatomy during surgery
    • Allows accurate mapping of critical brain regions
    • Helps our physicians remove tumors, seizure foci and other lesions
    • Reduces the need for repeated epilepsy surgeries

More about our EMU

Advanced diagnostics

Cook Children's offers some of the most advanced, kid-friendly care in the nation. With leading-edge imaging and diagnostic capabilities, our specialists are able to better treat patients and help them get back to doing what they do best: being kids.


The Neurodiagnostic Center at Cook Children's offers the most innovative and advanced technologies to diagnose, evaluate, and treat the conditions that affect a child's brain and development. At Cook Children's, you'll have access to leading-edge resources, brilliant doctors, and a team of highly skilled medical professionals who specialize in pediatric neurology. All with one purpose in mind: to help your child have the best quality of care possible.

Explore our neurodiagnostics


The iMRI suite is a special operating room developed for brain surgery. It combines innovative surgical and imaging tools in one place. Surgeons can take high-quality MRIs during surgery to see the area of the brain they are operating on, the size and shape of tumors, and the difference between healthy and unhealthy tissue. And because surgeons have the ability to see and remove the entire tumor during one surgery, these tools make surgery more precise, reducing risk and the need for a second surgery.

iMRI and real-time surgery


A breakthrough development in magnetic imaging technology, the MEG makes finding and diagnosing a brain condition much easier for our doctors. Billions of neurons fire off trillions of electric signals, making the brain a very busy place. The MEG maps all of that activity so that doctors can pinpoint with incredible accuracy where in the brain the seizure is occurring and what removing tissue from that area may affect, like speech. This helps to determine the best course of treatment for each patient.

Navigating the brain with MEG


Designed especially for patients with difficult to diagnose and control seizures, our advanced Epilepsy Monitoring Unit (EMU) offers the latest in high-tech evaluation tools. State-of-the-art wireless technology lets our team of highly trained EEG technologists record a child's brain activity while they do normal kid activities: visiting with other patients on the unit or in the play area, playing games, doing crafts, and sleeping. All in a safe environment surrounded by a specialized care team.

Our EMU improves outcomes

3D modeling

3D modeling offers a unique dimension in the diagnosis and treatment of brain conditions. Advanced techniques create an actual 3D image of your child's brain. The neuro team then uses this image to map the location of tumors, epileptic seizures, and other neurologic conditions. This is especially useful in pinpointing a surgical area and determining the best course of treatment for your child.

Brain mapping with 3-D modeling


The Comprehensive Epilepsy Program at Cook Children's is recognized as one of the leading programs in the nation. The commitment care, treatment, research and work to find cures for kids with epilepsy have helped us earn many designations, including:

Along with our neurosciences programs, we also work collaboratively with other organizations, and children's hospitals, such as the Pediatric Epilepsy Research Consortium (PERC) to improve care and outcomes, not only for our patients, but for all children who are diagnosed with epilepsy.

Neurologist with boy in wheelchair

The Jane and John Justin Neurosciences Center at Cook Children's has long been a leader in quality care of nervous system diseases, evidenced by first class programs to treat epilepsy, movement disorders, stroke, headaches, brain tumors and more. Through the support of donors and the dedication of our faculty, our programs have pioneered technologies such as deep brain stimulation for childhood dystonias and robot-assisted minimally invasive laser ablations to treat epilepsy.

We invite you to learn more about epilepsy and the services, research, clinical trials and support services available to you and your child here at Cook Children's. See what we're doing to give your child the very best opportunities in childhood—and adulthood.


Cynthia G. Keator, M.D., discusses epilepsy surgery evaluations.
Saleem I. Malik, M.D., on sudden unexplained death in epilepsy.
Cynthia G. Keator, M.D., on the unique advantages of Video EEGs.
M. Scott Perry, M.D., answers the most common epilepsy question.
Dr. Saleem Malik, M.D., explains available epilepsy treatment options.
M. Scott Perry, M.D. tells what to expect during a surgical evaluation.

We're here to help.

If your child has been diagnosed, you probably have lots of questions. We can help. If you would like to schedule an appointment, refer a patient or speak to our staff, please call our offices at 682-885-2500.